Contact Information
David Rickman, Ph.D.
Associate Professor of Research in Pathology and Laboratory Medicine
Department of Pathology and Laboratory Medicine
Weill Cornell Medical College
1300 York Avenue
Belfer 1528
New York, NY 10021
The Oncogenic Transcription Factors in Prostate Cancer laboratory is focused on elucidating the role of oncogenic transcription factors (e.g. ETS family members and N-Myc) in coordinating gene regulation, chromatin 3D architecture and response to chemotherapy in the context of prostate adenocarcinoma and neuroendocrine prostate cancer.
Active Projects
- The role of ERG in mediating taxane resistance.
- The role of N-Myc in driving the neuroendocrine prostate cancer phenotype.
- Development of in vitro and in vivo model systems of oncogenic transcription factor over-expression and other genomic alterations in prostate cancer.